Daddy Wronglegs was a spider like extraterrestrial that dealt designer drugs to humans, having come to Earth during the Maximum Security story arc. His buyers didn't know that the drugs he sold were laced with poison extracted from his fangs. Once consumed, his victims mutated into spider like monsters that followed his orders. The Punisher found him and overpowered the monster, using his skill with firearms to avoid having the beast bite and mutate him.
 
The Fantastic Four devised a cure for his victims after analyzing his venom, and then constructed a prison  to house the alien menace.
 

Powers

Daddy Wronglegs had a spider like physiology that gave him a healing ability, and enhanced strength and durability. He could generate webbing that ensnared foes. His large fangs and claws were very sharp, and generated a poison that mutated humans into spider monsters like him.