Jesse and company search for clues that will lead them to God, while officer John Tool--the unluckiest cop in the world--tries to track down the serial killer running amok in New York City. Their quests converge unexpectedly when the killer's identity is revealed!

Jesse and Tulip try to come to terms with their relationship as it stands; Si starts doing some research; Detective Tool gets a lead in the Reaver-Cleaver case, but his partner is nowhere to be found; Cassidy learns the truth about his old friend.