The Ghosts Annuals event continues as Wonder Woman is haunted by one of her oldest friends from Man's World! Wonder Woman is visited by the ghost of her old friend, Myndi Mayer, which sends her back to her old haunt in Boston, seeking the reason for this supernatural sighting. There, she seeks out the assistance of another old friend, police detective Ed Indelicato. Together, Diana and Ed follow the ghost's trail to Myndi's sister, a drug addict about to destroy her life with a new memory-destroying drug rooted in mythology.