It's been 15 years since the death of Mistress Nyx, and the world is slowly recovering - but this isn't a world we've ever seen before. This is a world where the natural and the supernatural have merged to create a dangerous new place - a world very much in need of Vampirella. In the city of Sepulcher, a delicate balance exists between humanity and the monstrous. It's a balance maintained by Vampirella and the agents of the Danse Macabre. But something has been unleashed in the city: living weapons birthed in the deepest regions of Hell. They're weapons so deadly they threaten all life within the great city's walls...and possibly the world beyond it.