Prince Drakken, leader of the Vampire Nation, has finally accomplished his goal of wresting control of the symbiotes away from the WetWorks team. Pilgrim, Jester, Claymore and Dozer have all been captured, while Dane has been taken by the Blood Queen, who hopes to reclaim the Vampire throne for herself. Unfortunately, time is running out. For Dozer has since been transformed into a giant pyramid in the heart of Phoenix, through which Drakken is now channeling the combined symbiote energy of WetWorks to produce a dangerous and expanding energy field that is rapidly giving Drakken control over the United States...