For Dave Lizewski and the self-made superheroes of NYC, sh*t just got really real. The Red Mist, now known as the Mother****er, has assembled his own team of Toxic Mega-***** and they're striking the heroes where they're most vulnerable: Their loved ones. If Kick-Ass wants to put a stop to the supervillain rampage, he's going to need the help of Mindy McCready, the one and only Hit-Girl.