PETER PARKER's got a real shot - a chance for a spot in a competitive Empire State University program as a high school student. Nothing's going to keep him from his goal...unless the old Parker luck strikes again! And a crime boss's interference with an experiment of DR. CURT CONNORS threatens to do just that, as an unexpected run-in heralds the return of the deadly LIZARD! But if SPIDER-MAN is going to save the day, does that mean Peter Parker will have to sacrifice his future? A tale of great power and the cost of responsibility in the mighty Marvel manner!