After the fall of the Angel Base, Storm and Colossus find themselves on the run. Will the murder of a human bring them closer together or drive them apart? Meanwhile, a cure is offered to mutantkind. Which X-Men will take it? Who does not? [Kitty Pryde does not appear in this issue, but orchestrates an attack behind the scenes which plays a significant role in the story and is named several times.]

Story by Brian Wood with art by Carlo Barberi and Don Ho.