Michelle Czajkowski is best known for her work on the long-running webcomic series Ava's Demon, about a young girl who has had a demon living inside of her for her entire life. The comic touches on themes of depression, love and suicide, set against a grand fantasy/sci-fi backdrop, and has received praise for its strong character work and painterly art style.

Czajkowski has also contributed artwork to the Bravest Warriors and Adventure Time comic series.

Her latest project is contributing artwork for the tabletop role-playing game Firelight. She will be creating character art and environmental art for the game.

She also continues to update Ava's Demon as the story moves towards its ending.