The Evil Horde is a team lead by Hordak. They are based on Etheria and fights He-Man and the Masters of the Universe and Skeletor and the Evil Warriors and of course She-Ra and the Great Rebelion.

Three Kryptionian brothers who wanted to rule Krypton.

A new powerful criminal organization in Marvel comics. Led by Stephanie Gerard and Chris Poulsen, the organization is poised to eliminate the last opposition and assume complete control of criminal enterprise in New York. Organization consists of former agents of A.I.M., HYDRA, Hive and etc.

A branched-off organization of Weapon X when it was temporarily shut down. This is the agency that created feral women like Native, Kimura and X-23.

The Fallen were a group of supernatural beings who once fought against Zarathos but later joined him in his fight for the Medallion of Power.

Though almost never truly united under one banner, The Fallen are those angels who parted ways with The Host and abandoned Heaven.

The Fallen consist of Brande, Tobruk, Exotica and Christie Blaze who act as protectors and guides to Max Faraday during his time in the Hollow Realm.

The Fangs are a group of mercenaries and killers lead by Viper. The group consist of Slither, Heat-Ray, Razorblade and Bludgeon.

A team consisting of four former members of the Liberteens who model themselves after the Fantastic Four, whom have been absent for a few years.

A team of criminals made up of Blue Streak and accomplices with suits similar to his.

The first enemy of the Golden Age Flash.

The Victor Von Doom's team and family in the House of M's reality

A cult who worship Superman.

A gang of five women. Their turf is the Old Beach borough.

Group of bird-like species that walks on two legs and talk like humans.

The Finders of the Lost are a cult of brainwashed followers of Father Lost, a Tanishan madman, and enemy of Batwing.

An elite group of the Brood. They are the actual offspring of the Brood Empress and have no host bodies. The Firstborn operate as the Brood Empress' personal assassins and are fanatically devoted to her.

Once the Galactic Empire fell, it officially surrendered. But it's legacy endured, and many Imperialists fled to the Unknown Regions away from the New Republic's reach, slowly rebuilding itself under the name of the First Order, loyal to the principles of the New Order, with new zealous officers in it's ranks and more advanced technology than it's predecessors under Supreme Leader Snoke's guidance. And now it is ready to reclaim the Imperial legacy.

A group dedicated to standing against The Hand

The Five are a circuit of mutants whose powers, working in tandem, can resurrect deceased mutants. They are a pillar of Krakoan society and serve as a symbol of mutant ingenuity and resilience.

Five beings from a probable future. They are powerful enough to conquer full systems in the year 3000.

The Five Fists were masked Chinese warriors active in the 1920s, in Astro City.

The Five Symbiotes are the offspring of Venom, extracted from the Venom symbiote and artificially aged to maturity by Roland Treece and the Life Foundation. Together they are a very powerful force who first served as soldiers for the Life Foundation. Currently, they are only four, after Scream betrayed them to fight back against the invasion of Knull.

Five criminal wives pooled their recourses in an effort to kill The Punisher once and for all.

An indie-rockband from the state of Oklahoma, whom guest appeared in the X-Men '92 comic

They're just a babe, a board, and a bike.

The Flock is made up of six flying children Max, Fang, Iggy, Nudge, Gazzy the Gasman and Angel. They are a result of an experiment and somehow have to save the world.

The talking flowers from Alice in Wonderland.

The evil human forms of flowers that occupy in Wonderland.

The Forgiven are a team of vampire superheroes. They no longer feel bloodlust and have special gadgets that protect them from sunlight.

.

A team of villains formed by Enchantress to dominate the Universe. They were stopped by a counterpart superhero team of lesser powered heroes known as "The Forgotten Heroes" and Superman.

The Forsaken are a dissident faction of the Scourge. Led by Sylvanas Windrunner, the Forsaken are established in the catacombs of Lordaeron.

A criminal syndicate of Los Angeles.

A mystic cabal dating back to at least 1776 and the American Revolution.

Velma's four brothers.

A group of space travelers in the 20th century who returned with great power and great ambition....

The Four are villainous foes of Youngblood.

Buzz, Pudge, Tommy & Tim.

The Four Horsemen are a group of Dead Knights and protectors of Naxxramas.

A group of four friends who made their own rules. An encounter with the First Fallen ported them to another dimension.

A Nazi themed group of supervillains. Most are retreads from MLJ comics in the 40's.

The Fraction are an interdimensional raiding empire. They roam the Multiverse following the trail of the Speed Force in search of worlds to plunder.

Mafia family set in New York

The Fraternity is the group of ruthless super-villains that rule the world of Millarworld. They originally consist of 5 separate families, ruling different parts of the world. Currently, Wesley Gibson has taken over after Mister Rictus' failed coup d'état against the ruling families.